2-(7-Amino-8-methoxy-1,2,4,5-tetrahydro-3-benzazepin-3-yl)-1-(4-methyl-piperazin-1-yl)-ethanone → 3-[[5-chloro-2-[[7-methoxy-3-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,2,4,5-tetrahydro-3-benzazepin-8-yl]amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:19])[c:6]([NH:8][CH:9]2[CH:10]([C:16](=[O:17])[NH2:18])[CH:11]3[CH:12]=[CH:13][CH:14]2[CH2:15]3)[n:7]1.[NH2:20][c:21]1[cH:22][c:23]2[c:24]([cH:40][c:41]1[O:42][CH3:43])[CH2:25][CH2:26][N:27]([CH2:30][C:31](=[O:32])[N:33]1[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]1)[CH2:28][CH2:29]2>>[c:2]1([NH:20][c:21]2[cH:22][c:23]3[c:24]([cH:40][c:41]2[O:42][CH3:43])[CH2:25][CH2:26][N:27]([CH2:30][C:31](=[O:32])[N:33]2[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]2)[CH2:28][CH2:29]3)[n:3][cH:4][c:5]([Cl:19])[c:6]([NH:8][CH:9]2[CH:10]([C:16](=[O:17])[NH2:18])[CH:11]3[CH:12]=[CH:13][CH:14]2[CH2:15]3)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-63b37c90629a494b9c630b3f0d5103c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…