Isobutylamine → HCID 68774481, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([C:12]([OH:14])=O)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[CH2:15]([NH2:19])[CH:16]([CH3:18])[CH3:17]>>[CH2:15]([NH:19][C:12]([C:9]1([C:6]2[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=2)[CH2:10][CH2:11]1)=[O:14])[CH:16]([CH3:18])[CH3:17]Participants
3
Procedure
Prepared in a similar manner to Example 35a starting from 1-(4-methoxyphenyl) cyclopropanecarboxylic acid and isobutyl amine. Yield: 97%. MS+H (248).
Workup
- customPrepared in a similar manner to Example 35a
Sources & evidence
- ORD record
- ord-4b29fc05270649618ad5a14a5b3ca9eb
- Source dataset
- uspto-grants-2010_11
- Patent number
- US07842324B2
Reaction notes
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