Isobutylamine → HCID 86609792, compound

HRID 1175619Notes

Reaction equation

HRID 1175619 reaction equation
[Br:1][C:2]1[N:7]=[CH:6][C:5]([C:8]([CH3:13])([CH3:12])[C:9]([OH:11])=O)=[CH:4][CH:3]=1.[CH2:14]([NH2:18])[CH:15]([CH3:17])[CH3:16]>>[Br:1][C:2]1[N:7]=[CH:6][C:5]([C:8]([CH3:13])([CH3:12])[C:9]([NH:18][CH2:14][CH:15]([CH3:17])[CH3:16])=[O:11])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6558IsobutylamineHCID 86609793HCID 86609793, compound

Product 1

HCID 86609792HCID 86609792, compoundYield 93%

Procedure

Prepared in a similar manner to Example 35a from 2-(6-Bromopyridin-3-yl)-2-methylpropanoic acid (example 40b) and isobutyl amine. Yield: 93%. MS+H (300).

Sources & evidence

ORD record
ord-39e14bfa3d3d4789ad2b6fde4e2543e4
Source dataset
uspto-grants-2010_11
Patent number
US07842324B2

Reaction notes

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