HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile → HCID 68775072, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile | HCID 16414216 | — |
| Reactant | HCID 68778103 | HCID 68778103 | — |
| Product | HCID 68775072 | HCID 68775072 | 49% |
Reaction Steps
Prepared in a similar manner to Example 23 from 2-(5-bromopyridin-2-yl)-N-isobutyl-2-methylpropanamide (example 42a) and 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile. Yield 49%. 1H NMR (400 MHz, acetonitrile-d6): δ 0.80-0.81 (d, 6H), 1.63 (s, 6H), 1.71-1.77 (m, 1H), 2.97-3.00 (t, 2H), 7.01 (bs, 1H), 7.59-7.62 (d, 1H), 8.18-8.21 (dd, 1H), 8.59-8.60 (t, 1H), 8.99 (d, 1H), 9.20-9.21 (d, 1H); MS+H (323).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842324B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-f99234d7279845989efaa51f8f68c274 |
| Source note | uspto-grants-2010_11 |