Isobutylamine → HCID 68778103, compound

HRID 1175626Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH3:13])([CH3:12])[C:9]([OH:11])=O)=[N:6][CH:7]=1.[CH2:14]([NH2:18])[CH:15]([CH3:17])[CH3:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH3:13])([CH3:12])[C:9]([NH:18][CH2:14][CH:15]([CH3:17])[CH3:16])=[O:11])=[N:6][CH:7]=1

Participants

Reactant 2

HCID 6558Isobutylamine

HCID 53403683HCID 53403683, compound

Product 1

HCID 68778103HCID 68778103, compoundYield 32%

Procedure

Prepared in a similar manner to example 27 from 2-(5-bromopyridin-2-yl)-2-methylpropanoic acid (example 46b) and isobutyl amine. Yield 32%. MS+H (301).

Sources & evidence

ORD record: ord-cd2d9369708b409e96f073713b80f46b
Source dataset: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07842324B2

Reaction notes

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