HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furfurylamine → 2-(4-(6-cyanopyrazin-2-yl)phenyl)-N-(furan-2-ylmethyl)-2-methylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furfurylamine | HCID 3438 | — |
| Reactant | 2-(4-(6-Cyanopyrazin-2-yl)phenyl)-2-methylpropanoic acid | HCID 68776443 | — |
| Product | 2-(4-(6-cyanopyrazin-2-yl)phenyl)-N-(furan-2-ylmethyl)-2-methylpropanamide | HCID 68776556 | 30% |
Reaction Steps
Prepared in a similar manner to Example 20 from 2-(4-(6-Cyanopyrazin-2-yl)phenyl)-2-methylpropanoic acid (example 20a) and furan-2-ylmethanamine. Yield 30%. 1H NMR (400 MHz, dMSO): δ 1.51 (s, 6H), 4.23-4.25 (d, 2H), 6.06-6.07 (d, 1H), 6.34-6.35 (t, 1H), 7.48-7.50 (d, 2H), 7.53 (t, 1H), 7.97-8.00 (t, 1H), 9.16 (s, 1H), 9.56 (s, 1H); MS+H (347).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842324B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-3df2fe70493843cc9d7710ccdd830033 |
| Source note | uspto-grants-2010_11 |