Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1175640Generated: October 31, 2026

2-Amino-1-butanol → (S)-2-(4-(6-cyanopyrazin-2-yl)phenyl)-N-(1-hydroxybutan-2-yl)-2-methylpropanamide

https://huagongshe.com/reaction/1175640

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1-butanolHCID 22129—
Reactant2-(4-(6-Cyanopyrazin-2-yl)phenyl)-2-methylpropanoic acidHCID 68776443—
Product(S)-2-(4-(6-cyanopyrazin-2-yl)phenyl)-N-(1-hydroxybutan-2-yl)-2-methylpropanamideHCID 6877485037%

Reaction Steps

Prepared in a similar manner to Example 20 from 2-(4-(6-Cyanopyrazin-2-yl)phenyl)-2-methylpropanoic acid (example 20a) and 2-aminobutan-1-ol. Yield 37%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842324B2
Source datasetuspto-grants-2010_11
ORD IDord-fb89cedf3bb84586ab9f2be8d1a0c51d
Source noteuspto-grants-2010_11