Nitric Acid → HCID 16638331, compound

HRID 1175677Notes

Reaction equation

HRID 1175677 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]21[C:13](=[O:14])[NH:12][C:11](=[O:15])[NH:10]2.[N+:16]([O-])([OH:18])=[O:17]>>[N+:16]([C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[CH2:1][C:2]1([C:13](=[O:14])[NH:12][C:11](=[O:15])[NH:10]1)[CH2:3]2)([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 2799991',3'-dihydrospiro[imidazolidine-4,2'-indene]-2,5-dione

Product 1

HCID 16638331HCID 16638331, compound

Procedure

To a solution of conc. HNO3 (30 ml) at 0° C. was added 1′,3′-dihydrospiro[imidazolidine-4,2′-indene]-2,5-dione (3 g) in portions. The cooling bath was removed and the reaction mixture was stirred at room temperature for 1.5 h. The reaction mixture was poured into ice and the precipitated product was filtered, washed with water and desiccated. LC/MS (10% to 99%): M/Z (M+H)+ (obs)=248; tR=1.82.

Workup

  1. customThe cooling bath was removed
  2. additionThe reaction mixture was poured into ice
  3. filtrationthe precipitated product was filtered
  4. washwashed with water

Sources & evidence

ORD record
ord-2a0eedd5cf10410fa755f5f49f38e158
Source dataset
uspto-grants-2010_11
Patent number
US07842686B2

Reaction notes

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