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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1175902Generated: October 31, 2026

2-(Azetidin-1-ylcarbonyl)-5-bromopyridine → 3-{[6-(azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-N-(1-ethyl-1H-pyrazol-3-yl)-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamide

https://huagongshe.com/reaction/1175902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Azetidin-1-ylcarbonyl)-5-bromopyridineHCID 53629617—
ReactantN-(1-Ethyl-1H-pyrazol-3-yl)-3-hydroxy-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamideHCID 59127176—
Product3-{[6-(azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-N-(1-ethyl-1H-pyrazol-3-yl)-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamideHCID 16039686—

Reaction Steps

The preparation of N-(1-ethyl-1H-pyrazol-3-yl)-3-hydroxy-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamide and 2-(azetidin-1-ylcarbonyl)-5-bromopyridine was described earlier.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842694B2
Source datasetuspto-grants-2010_11
ORD IDord-46df46d855ee4ad3b7ec0e91f9bd09b9
Source noteuspto-grants-2010_11