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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1175974Generated: October 30, 2026

Tetrahydrofuran-3-YL 4-methylbenzenesulfonate, (3R)- → (S)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate

https://huagongshe.com/reaction/1175974

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuran-3-YL 4-methylbenzenesulfonate, (3R)-HCID 11149197—
Reactant3-(Benzyloxy)-5-hydroxy-N-(1-methyl-1H-pyrazol-3-yl)benzamideHCID 59127119—
Product(S)-tetrahydrofuran-3-yl 4-methylbenzenesulfonateHCID 13837326—

Reaction Steps

The preparation of 3-hydroxy-N-(1-methyl-1H-pyrazol-3-yl)-5-[(phenylmethyl)oxy]benzamide was described earlier. (3S)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate was prepared in an analogous fashion to (3R)-tetrahydrofuran-3-yl 4-methylbenzenesulfonate, as described in Example 25.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842694B2
Source datasetuspto-grants-2010_11
ORD IDord-9b74f4a87ef74228a424277a595107fa
Source noteuspto-grants-2010_11