3-Acetaminobenzyl alcohol → HCID 68501875, compound

HRID 1176224Notes

Reaction equation

HRID 1176224 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:12])[CH3:11])[CH:6]=[CH:7][CH:8]=1.Cl[CH2:14][CH2:15][CH2:16][O:17][CH3:18]>>[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([N:9]([CH2:14][CH2:15][CH2:16][O:17][CH3:18])[C:10](=[O:12])[CH3:11])[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 966393-Acetaminobenzyl alcoholHCID 1189271-Chloro-3-methoxypropane

Product 1

HCID 68501875HCID 68501875, compound

Procedure

Analogously to Example 8c, 0.40 g of N-(3-hydroxymethylphenyl)acetamide and 0.978 ml of 1-chloro-3-methoxypropane are reacted. The title compound is obtained as a beige oil. Rf=0.17 (6:1 EtOAc-heptane); Rt=2.55.

Sources & evidence

ORD record
ord-4c84190ed46b4c0abab583a05908b944
Source dataset
uspto-grants-2010_11
Patent number
US07842688B2

Reaction notes

Loading…