1-Chloro-3-methoxypropane → HCID 68501422, compound

HRID 1176239Notes

Reaction equation

HRID 1176239 reaction equation
[OH:1][CH2:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][C:9](=[O:13])[NH:10]2)=[CH:5][CH:4]=1.Cl[CH2:15][CH2:16][CH2:17][O:18][CH3:19]>>[CH3:19][O:18][CH2:17][CH2:16][CH2:15][O:13][C:9]1[CH:8]=[CH:7][C:6]2[C:11](=[CH:12][C:3]([CH2:2][OH:1])=[CH:4][CH:5]=2)[N:10]=1

Participants

3

Reactant 2

HCID 1189271-Chloro-3-methoxypropaneHCID 68498996HCID 68498996, compound

Product 1

HCID 68501422HCID 68501422, compound

Procedure

Analogously to Example 2c, 2.66 g of 7-hydroxymethyl-1H-quinolin-2-one are reacted with 3.34 ml of 1-chloro-3-methoxypropane. The title compounds are obtained as slightly yellowish oils.

Sources & evidence

ORD record
ord-94f4f3486ccd4d7cb37fd738a8ee8a52
Source dataset
uspto-grants-2010_11
Patent number
US07842688B2

Reaction notes

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