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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176255Generated: October 30, 2026

2-(2-Hydroxyethyl)phenol → HCID 68505010, compound

https://huagongshe.com/reaction/1176255

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Hydroxyethyl)phenolHCID 82200—
ReactantTert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylateHCID 86609984—
ProductHCID 68505010HCID 68505010—

Reaction Steps

Analogously to Method G, 5.00 g of tert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylate (Example 14b) and 0.99 g of 2-(2-hydroxyethyl)phenol are reacted. The title compound is obtained as a colourless oil. Rf=0.08 (1:2 EtOAc-heptane); Rt=5.81.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-5eb696172b8a4d10a1c8cc9d60ed5cb9
Source noteuspto-grants-2010_11