HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19593725, compound → tert-Butyl 3-{1(S)-[2-(2-acetylaminoethyl)phenylcarbamoyl]ethoxy}-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19593725 | HCID 19593725 | — |
| Reactant | tert-butyl 3-(1(S)-carboxyethoxy)-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate | HCID 68497739 | — |
| Product | tert-Butyl 3-{1(S)-[2-(2-acetylaminoethyl)phenylcarbamoyl]ethoxy}-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate | HCID 68502341 | — |
Reaction Steps
Analogously to Example 3a, 0.175 g of tert-butyl 3-(1(S)-carboxyethoxy)-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate and 0.065 g of N-[2-(2-aminophenyl)ethyl]acetamide (Example 34c) are reacted. The title compound is obtained as a brown oil. Rf=0.35 (95:5 dichloromethane-methanol); Rt=5.32.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842688B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-7e0948c8699845c9b9bf49e5c6eb1f1e |
| Source note | uspto-grants-2010_11 |