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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176297Generated: November 3, 2026

Methyl 3-(2-hydroxyphenyl)propionate → HCID 68499148, compound

https://huagongshe.com/reaction/1176297

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(2-hydroxyphenyl)propionateHCID 2794569—
ReactantTert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylateHCID 86609984—
ProductHCID 68499148HCID 68499148—

Reaction Steps

Analogously to Method F, 0.30 g of tert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylate (Example 14b) and methyl 3-(2-hydroxyphenyl)propionate are used to prepare the title compound as a colourless oil. Rf=0.23 (1:2 EtOAc-heptane); Rt=6.20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-07d1264269bf426ab7c6641eccaa5988
Source noteuspto-grants-2010_11