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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176300Generated: November 1, 2026

2-(3-hydroxypropyl)phenol → HCID 68499004, compound

https://huagongshe.com/reaction/1176300

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-hydroxypropyl)phenolHCID 266742—
ReactantTert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylateHCID 86609984—
ProductHCID 68499004HCID 68499004—

Reaction Steps

Analogously to Method F, 2.24 g of tert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(toluene-4-sulphonyloxy)ethoxy]piperidine-1-carboxylate (Example 14b) and 1.28 g of 2-(3-hydroxypropyl)phenol are reacted. The title compound is obtained as a colourless oil. Rf=0.41 (2:1 EtOAc-heptane); Rt=5.90.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-23368dbf958941df9e6058b08bb2f1cb
Source noteuspto-grants-2010_11