HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate → tert-Butyl 3-hydroxy-4-(4-{2-[2-(2-methoxyphenyl)ethoxy]ethoxy}phenyl)piperidine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate | HCID 21713087 | — |
| Edukt | 2-[2-(2-Methoxyphenyl)ethoxy]ethyl toluene-4-sulphonate | HCID 86609999 | — |
| Produkt | tert-Butyl 3-hydroxy-4-(4-{2-[2-(2-methoxyphenyl)ethoxy]ethoxy}phenyl)piperidine-1-carboxylate | HCID 68506643 | — |
Reaktionsschritte
Analogously to Method I, 0.610 g of tert-butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate and 0.808 g of 2-[2-(2-methoxyphenyl)ethoxy]ethyl toluene-4-sulphonate (Example 45b) are reacted. The title compound is obtained as a slightly yellowish oil. Rt=5.10.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07842688B2 |
| Quelldatensatz | uspto-grants-2010_11 |
| ORD ID | ord-a82b35a47bb84e96bc6aa82288f52643 |
| Quellennotiz | uspto-grants-2010_11 |