3-Hydroxy-4-methylbenzoic acid → HCID 68500503, compound

HRID 1176396Notes

Reaction equation

HRID 1176396 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[CH3:11])[C:5]([OH:7])=[O:6].I[CH2:13][CH2:14][O:15][Si:16]([CH:23]([CH3:25])[CH3:24])([CH:20]([CH3:22])[CH3:21])[CH:17]([CH3:19])[CH3:18]>>[CH3:11][C:10]1[CH:9]=[CH:8][C:4]([C:5]([O:7][CH2:13][CH2:14][O:15][Si:16]([CH:23]([CH3:25])[CH3:24])([CH:20]([CH3:22])[CH3:21])[CH:17]([CH3:19])[CH3:18])=[O:6])=[CH:3][C:2]=1[O:1][CH2:13][CH2:14][O:15][Si:16]([CH:20]([CH3:21])[CH3:22])([CH:17]([CH3:19])[CH3:18])[CH:23]([CH3:24])[CH3:25]

Participants

3

Reactant 2

HCID 685123-Hydroxy-4-methylbenzoic acidHCID 11450272(2-Iodoethoxy)triisopropylsilane

Product 1

HCID 68500503HCID 68500503, compound

Procedure

Analogously to Example 12d, 5.0 g of 3-hydroxy-4-methylbenzoic acid and 24.3 g of (2-iodoethoxy)triisopropylsilane are reacted. The title compound is obtained as a yellowish oil. Rf=0.66 (1:4 EtOAc-heptane); Rt=6.30.

Sources & evidence

ORD record
ord-8d4d2bd779504b96a1997431f8689c66
Source dataset
uspto-grants-2010_11
Patent number
US07842688B2

Reaction notes

Loading…