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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176405Generated: October 31, 2026

1-(3-bromopropoxy)-2-chlorobenzene → HCID 54490977, compound

https://huagongshe.com/reaction/1176405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-bromopropoxy)-2-chlorobenzeneHCID 2734933—
Reactant(3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylateHCID 21713087—
ProductHCID 54490977HCID 54490977—

Reaction Steps

Analogously to Method I, 5.84 g of tert-butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate and 6.00 g of 1-(3-bromopropoxy)-2-chlorobenzene are reacted. The title compound is obtained as a white solid. Rf=0.62 (1:2 EtOAc-heptane); Rt=5.33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-869508e51df347d29f9b538343979075
Source noteuspto-grants-2010_11