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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176450Generated: October 31, 2026

1-Chloro-3-methoxypropane → 1-Ethoxy-2-(3-methoxypropoxy)-4-methylbenzene

https://huagongshe.com/reaction/1176450

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-3-methoxypropaneHCID 118927—
Reactant2-Ethoxy-5-methylphenolHCID 12257123—
Product1-Ethoxy-2-(3-methoxypropoxy)-4-methylbenzeneHCID 59224074—

Reaction Steps

Analogously to Method F, 5.05 g of 2-ethoxy-5-methylphenol and 4.03 g of 1-chloro-3-methoxypropane are reacted. The title compound is obtained as a slightly orange oil. Rf=0.32 (1:4 EtOAc-heptane); Rt=4.60

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-e8f831e06a64461f841a0442eed89817
Source noteuspto-grants-2010_11