HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+)-Epichlorohydrin → HCID 87475792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+)-Epichlorohydrin | HCID 149428 | — |
| Reactant | Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylate | HCID 15546933 | — |
| Product | HCID 87475792 | HCID 87475792 | — |
Reaction Steps
Analogously to Example 148e, 5.60 g of tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}piperidine-1-carboxylate and 2.05 ml of (S)-(+)-epichlorohydrin are reacted. The title compound is obtained as a colourless oil. Rf=0.24 (1:2 EtOAc-heptane); Rt=5.66.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842688B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-cc19e4bfdde1413aaa58cf644e0d6246 |
| Source note | uspto-grants-2010_11 |