Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176473Generated: October 31, 2026

1-(3-Bromopropoxy)-2,4-difluorobenzene → HCID 68501615, compound

https://huagongshe.com/reaction/1176473

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Bromopropoxy)-2,4-difluorobenzeneHCID 10857914—
Reactant(3S,4S)-tert-Butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylateHCID 21713087—
ProductHCID 68501615HCID 68501615—

Reaction Steps

Analogously to Method I, 0.750 g of tert-butyl 3-hydroxy-4-(4-hydroxyphenyl)piperidine-1-carboxylate and 0.796 g of 1-(3-bromopropoxy)-2,4-difluorobenzene are reacted. The title compound is obtained as a slightly yellowish oil. Rf=0.13 (1:2 EtOAc-heptane); Rt=5.12.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842688B2
Source datasetuspto-grants-2010_11
ORD IDord-91df5dc3b81e42d3bc439b9827c10a7a
Source noteuspto-grants-2010_11