HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(chloromethyl)-4-(3-methoxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one → HCID 68502038, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(chloromethyl)-4-(3-methoxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | HCID 46835223 | — |
| Reactant | HCID 68497737 | HCID 68497737 | — |
| Product | HCID 68502038 | HCID 68502038 | — |
Reaction Steps
Analogously to Method D, 0.510 g of tert-butyl 4-{4-[3-(3,5-difluorophenoxy)propoxy]phenyl}-3-hydroxypiperidine-1-carboxylate and 0.323 g of 6-chloromethyl-4-(3-methoxypropyl)-4H-benzo[1,4]oxazin-3-one (Example 2a) are reacted. The title compound is obtained as a yellowish oil. Rf=0.23 (1:1 EtOAc-heptane); Rt=6.04.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842688B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-71e2596bc8634ce494b10b7d2f50123f |
| Source note | uspto-grants-2010_11 |