HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → tert-Butyl (R)-3-phenoxypyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | (S)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester | HCID 57957824 | — |
| Product | tert-Butyl (R)-3-phenoxypyrrolidine-1-carboxylate | HCID 86610018 | — |
Reaction Steps
Analogously to Method G, 1.01 g of tert-butyl (S)-3-(toluene-4-sulphonyloxy)pyrrolidine-1-carboxylate and 0.418 g of phenol are reacted. The title compound is obtained as a colourless oil. Rf=0.47 (2:1 EtOAc-heptane); Rt=4.88.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842688B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-899e7d21194b4ee38a7bff879b32f483 |
| Source note | uspto-grants-2010_11 |