HCID 68502342, compound → HCID 68499310, compound

HRID 1176561Notes

Reaction equation

HRID 1176561 reaction equation
C([N:8]1[CH2:12][CH2:11][C@@H:10]([N:13]([CH3:22])[C:14](=[O:21])[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:9]1)C1C=CC=CC=1>CO>[CH3:22][N:13]([C@@H:10]1[CH2:11][CH2:12][NH:8][CH2:9]1)[C:14](=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 1

HCID 68502342HCID 68502342, compound

Product 1

HCID 68499310HCID 68499310, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Analogously to Method B, 0.774 g of (R)—N-(1-benzylpyrrolidin-3-yl)-N-methylbenzamide in methanol is used to prepare the title compound. Rf=0.08 (200:20:1 dichloromethane-methanol-25% conc. ammonia); Rt=2.04.

Sources & evidence

ORD record
ord-20e9c34dbf84471389d5f9f861ce0149
Source dataset
uspto-grants-2010_11
Patent number
US07842688B2

Reaction notes

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