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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176750Generated: October 31, 2026

p-Bromobenzenesulfonyl chloride → (E)-3-[1-(4-bromo-benzenesulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl ester

https://huagongshe.com/reaction/1176750

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Bromobenzenesulfonyl chlorideHCID 7396—
Reactanttert-butyl (2E)-3-(1H-pyrrol-3-yl)prop-2-enoateHCID 66646340—
Product(E)-3-[1-(4-bromo-benzenesulfonyl)-1H-pyrrol-3-yl]-acrylic acid tert-butyl esterHCID 66646304—

Reaction Steps

Starting from compound D1 and 4-bromo-benzenesulfonyl chloride the title compound can be obtained analogously as described for compound D2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842820B2
Source datasetuspto-grants-2010_11
ORD IDord-7e35990294584152a19093646ddcddf8
Source noteuspto-grants-2010_11