Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176770Generated: October 26, 2026

Methyl 3-(bromomethyl)benzoate → 3-(4'-Methoxy-biphenyl-4-yloxymethyl)-benzoic acid

https://huagongshe.com/reaction/1176770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(bromomethyl)benzoateHCID 517981—
Reactant4-Hydroxy-4'-methoxybiphenylHCID 11030839—
Product3-(4'-Methoxy-biphenyl-4-yloxymethyl)-benzoic acidHCID 11359559—

Reaction Steps

3-(4′-Methoxy-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 4-hydroxy-4′-methoxybiphenyl (available from TCI America, Portland, Oreg.) and 3-(bromomethyl)benzoic acid methyl ester (available from Lancaster Synthesis Ltd., Morcambe, Lancashire, UK). Yield: 73 mg. Mass spectrum (ES) MH+=335.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842825B2
Source datasetuspto-grants-2010_11
ORD IDord-83b31947dcf2452d87b6423b0da0b4c8
Source noteuspto-grants-2010_11