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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176779Generated: October 31, 2026

Methyl 5-(chloromethyl)-2-furoate → 5-(2'-Nitro-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid

https://huagongshe.com/reaction/1176779

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 5-(chloromethyl)-2-furoateHCID 75065—
Reactant4-Hydroxy-2'-nitrobiphenylHCID 15541112—
Product5-(2'-Nitro-biphenyl-4-yloxymethyl)-furan-2-carboxylic acidHCID 11405035—

Reaction Steps

5-(2′-Nitro-biphenyl-4-yloxymethyl)-furan-2-carboxylic acid was prepared using general procedure A from 4-hydroxy-2′-nitrobiphenyl (available from TCI America, Portland, Oreg.) and 5-chloromethylfuran-2-carboxylic acid methyl ester (available from Aldrich, Milwaukee, Wis., or from Maybridge plc, Tintagel, UK). Yield: 82 mg. Mass spectrum (ES) MH+=340.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842825B2
Source datasetuspto-grants-2010_11
ORD IDord-bc97bfd3fcd0429ab0518f3fb11b14fd
Source noteuspto-grants-2010_11