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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176783Generated: October 31, 2026

Methyl 2-(bromomethyl)benzoate → 2-(2'-Nitro-biphenyl-4-yloxymethyl)-benzoic acid

https://huagongshe.com/reaction/1176783

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(bromomethyl)benzoateHCID 2734813—
Reactant4-Hydroxy-2'-nitrobiphenylHCID 15541112—
Product2-(2'-Nitro-biphenyl-4-yloxymethyl)-benzoic acidHCID 11291012—

Reaction Steps

2-(2′-Nitro-biphenyl-4-yloxymethyl)-benzoic acid was prepared using general procedure A from 4′-hydroxy-2-nitrobiphenyl (available from TCI America, Portland, Oreg.) and 2-bromomethyl-benzoic acid methyl ester (Intermediate 1). Yield: 69 mg. Mass spectrum (ES) MH+=350.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842825B2
Source datasetuspto-grants-2010_11
ORD IDord-305067321bcf4c3fbb78ba35fa1402ef
Source noteuspto-grants-2010_11