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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1176789Generated: October 31, 2026

3-Phenylphenol → 2-(Biphenyl-3-yloxymethyl)-thiazole-4-carboxylic acid

https://huagongshe.com/reaction/1176789

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PhenylphenolHCID 11381—
ReactantEthyl 2-(bromomethyl)-1,3-thiazole-4-carboxylateHCID 11043146—
Product2-(Biphenyl-3-yloxymethyl)-thiazole-4-carboxylic acidHCID 11243864—

Reaction Steps

2-(Biphenyl-3-yloxymethyl)-thiazole-4-carboxylic acid was prepared using general procedure B from 3-phenylphenol (available from Aldrich, Milwaukee, Wis.) and 2-bromomethyl-thiazole-4-carboxylic acid ethyl ester (Intermediate 3). Yield: 65 mg. Mass spectrum (ES) MH+=312.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842825B2
Source datasetuspto-grants-2010_11
ORD IDord-2aac22f3550243b3934d9008bb509318
Source noteuspto-grants-2010_11