HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 4,4'-dicyanobenzil
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4,4'-Dibromobenzil | HCID 96430 | — |
| Reactant | HCID 178418260 | HCID 178418260 | — |
| Product | 4,4'-dicyanobenzil | HCID 10978201 | 48% |
Reaction Steps
Here we have discovered that the compound can be easily synthesized from commercially available 4,4′-dibromobenzil. The reaction between 4,4′-dibromobenzil and copper cyanide in DMF at 165° C. yielded 4,4′-dicyanobenzil (JYC-I-097-A) as a yellow solid (1.36 g, 48%) after column chromatography. The scheme of the reaction is shown in FIG. 12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842830B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-039f4329f7f94b19991756b79995d8cb |
| Source note | uspto-grants-2010_11 |