2-Aminobenzenesulfonamide → 2-Amino-5-iodobenzenesulfonamide

HRID 1176976Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].[I:12]N1C(=O)CCC1=O>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([I:12])=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:9])=[O:10]

Participants

Reactant 2

HCID 728942-Aminobenzenesulfonamide

HCID 120273N-Iodosuccinimide

Product 1

HCID 223240882-Amino-5-iodobenzenesulfonamide

Procedure

Commercially available 2-amino-benzensulfonamide can be treated with N-iodosuccinimide to give the desired 2-amino-5-iodo-benzenesulfonamide intermediate.

Sources & evidence

ORD record: ord-9b9bfcae290b4ac39b0a1d6c8f4bc1f7
Source dataset: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07842838B2

Reaction notes

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