HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Malonate → N-(4-methanesulfonylamino-2-sulfamoyl-phenyl)-malonamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Malonate | HCID 7761 | — |
| Reactant | 2-Amino-5-[(methylsulfonyl)amino]benzenesulfonamide | HCID 24950657 | — |
| Product | N-(4-methanesulfonylamino-2-sulfamoyl-phenyl)-malonamic acid ethyl ester | HCID 24858398 | — |
Reaction Steps
2-Amino-5-methanesulfonylamino-benzenesulfonamide (prepared as described in schemes 4 and 12) can be treated with a dialkyl malonate, such as diethyl malonate, to afford the desired N-(4-methanesulfonylamino-2-sulfamoyl-phenyl)-malonamic acid ethyl ester intermediate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842838B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-2d3b471ad06146aa8e91b951e06fcc28 |
| Source note | uspto-grants-2010_11 |