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HRID1177120

反应详情

EQUATION

反应方程式

HRID 1177120 的结构方程式

REACTANTS

反应物

3
结构：CS(=O)(=O)c1ccc(F)c(Cl)c1
HCID21340880

2-Chloro-1-fluoro-4-(methanesulfonyl)benzene

C7H6ClFO2S

结构：COC(=O)c1cc(O)c2c(c1)OC(C)(C)C2
HCID25067323

Methyl 4-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-6-carboxylate

C12H14O4

结构：COC(=O)c1cc(Oc2ccc(S(C)(=O)=O)c(Cl)c2)c2c(c1)OC(C)(C)C2
HCID59560436

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1cc(Oc2ccc(S(C)(=O)=O)cc2Cl)c2c(c1)OC(C)(C)C2
HCID59560316

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a similar manner as described for Intermediate 118a, from 3-chloro-4-fluoro-1-(methylsulfonyl)benzene and 4-hydroxy-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid methyl ester (3e). 1H NMR (400 MHz, CDCl3) δ 8.07 (d, J=2.27 Hz, 1 H) 7.77 (dd, J=8.59, 2.27 Hz, 1 H) 7.29 (d, J=1.01 Hz, 1 H) 7.18 (d, J=1.26 Hz, 1 H) 6.98 (d, J=8.59 Hz, 1 H) 3.88 (s, 3 H) 3.10 (s, 3 H) 2.93 (s, 2 H) 1.50 (s, 6 H); LCMS for C19H19ClO6S m/z 411.00 (M+H)+.