HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1177166Generated: October 29, 2026
Ammonium Hydroxide → HCID 178480465, compound
https://huagongshe.com/reaction/1177166
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 4-(4-Cyano-3-fluoro-phenoxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide | HCID 66756101 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178480465 | HCID 178480465 | — |
Reaction Steps
To a solution of 4-(4-cyano-3-fluoro-phenoxy)-2,2-dimethyl-2,3-dihydro-benzofuran-6-carboxylic acid (1-methyl-1H-pyrazol-3-yl)-amide (183) (164 mg, 0.404 mmol) in 3 mL EtOH was added 1 mL 50% NH4OH in water. The resulting mixture was stirred at 55° C. for 2 hr, concentrated in vacuo, dried under vacuum, and used as it is for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07842713B2 |
|---|
| Source dataset | uspto-grants-2010_11 |
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| ORD ID | ord-f0f3637e3d8e4a7ca404e739f1aa221a |
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| Source note | uspto-grants-2010_11 |
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