HRID1177446

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21100040

Methyl azetidine-3-carboxylate--hydrogen chloride (1/1)

C5H10ClNO2

结构：O=Cc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)cc3s2)c(F)c1

HCID86638710

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C1CN(Cc2ccc(-c3nc4ccc(C5(c6ccccc6)CC5)cc4s3)c(F)c2)C1

HCID67111547

未命名化合物

PROCEDURE

实验过程

Reaction of 3-fluoro-4-(6-(1-phenylcyclopropyl)benzo[d]thiazol-2-yl)benzaldehyde (0.050 g, 0.13 mmol) and methyl azetidine-3-carboxylate hydrochloride (0.030 g, 0.20 mmol) according to Reference R and general procedure for reductive amination afforded methyl 1-((3-fluoro-4-(6-(1-phenylcyclopropyl)benzo[d]thiazol-2-yl)phenyl)methyl)azetidine-3-carboxylate. MS (ESI) m/z: Calculated: 472.2; Observed: 473.1 (M++1).