HuagongsheHuagongshe Chemistry Print Report · For research reference only
beta-Alanine, ethyl ester, hydrochloride → HCID 67111624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | beta-Alanine, ethyl ester, hydrochloride | HCID 458475 | — |
| Reactant | 3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzoic acid | HCID 57394406 | — |
| Product | HCID 67111624 | HCID 67111624 | — |
Reaction Steps
Reaction of 3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzoic acid (0.080 g, 0.20 mmol) and beta-alanine ethyl ester hydrochloride, according to Reference S and the general procedure for amide formation afforded ethyl 3-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzamido)propanoate. MS (ESI) m/z: Calculated: 489.2; Observed: 490.0 (M++1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07842685B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-ff546b2174064617adfea9213b7960b8 |
| Source note | uspto-grants-2010_11 |