HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Aminobutyrate ethyl hydrochloride → Ethyl 4-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzamido)butanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Aminobutyrate ethyl hydrochloride | HCID 12649661 | — |
| Edukt | 3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzoic acid | HCID 57394406 | — |
| Produkt | Ethyl 4-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzamido)butanoate | HCID 67111475 | — |
Reaktionsschritte
Reaction of 3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzoic acid (0.080 g, 0.20 mmol) and ethyl 4-aminobutyrate hydrochloride, according to Reference S and the general procedure for amide formation afforded ethyl 4-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzamido)butanoate. MS (ESI) m/z: Calculated: 503.2; Observed: 504.1 (M++1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07842685B2 |
| Quelldatensatz | uspto-grants-2010_11 |
| ORD ID | ord-addb85bb221a4b299b028b3046be0d2f |
| Quellennotiz | uspto-grants-2010_11 |