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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 117746Generated: October 31, 2026

Acetic Acid → N-[4-chloro-2-fluor-3-(2-hydroxyethyl)phenyl]-2,2-difluoro-2-phenylacetamide

https://huagongshe.com/reaction/117746

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantNitriteHCID 946—
ReactantWaterHCID 962—
ReactantCuprous chlorideHCID 62652—
ReactantN-[4-amino-2-fluoro-3-(2-hydroxyethyl)phenyl]-2,2-difluoro-2-phenylacetamideHCID 22475328—
ProductN-[4-chloro-2-fluor-3-(2-hydroxyethyl)phenyl]-2,2-difluoro-2-phenylacetamideHCID 22475352—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-d66d5c0e332347c1bb1dd86b8dc75eec
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)