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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1177604Generated: October 30, 2026

(R)-Homo-beta-alanine hydrochloride → HCID 67111813, compound

https://huagongshe.com/reaction/1177604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-Homo-beta-alanine hydrochlorideHCID 22982782—
Reactant3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzaldehydeHCID 59174907—
ProductHCID 67111813HCID 67111813—

Reaction Steps

Reaction of 3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzaldehyde (0.040 g, 0.11 mmol) and (R)-3-aminobutanoic acid hydrochloride (0.056 g, 0.40 mmol) according to Reference R and general procedure for reductive amination afforded (R)-3-(3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzylamino)butanoic acid hydrochloride. MS (ESI) m/z: calculated: 461.2; Observed: 462.1 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07842685B2
Source datasetuspto-grants-2010_11
ORD IDord-fa87dc09fb654121a5d004c59d97fd89
Source noteuspto-grants-2010_11