1-(Bromomethyl)-1-(methoxymethyl)cyclopropane → 1'-[(6-Chloro-1-{[1-(methoxymethyl)cyclopropyl]methyl}-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Reaction equation
[Br:28][CH2:29][C:30]1([CH2:33][O:34][CH3:35])[CH2:31][CH2:32]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:25])[c:19]5[c:20]4[cH:21][cH:22][cH:23][cH:24]5)[CH2:26][CH2:27]3)[cH:7][nH:8][c:9]2[cH:10]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][C:16]4([O:17][C:18](=[O:25])[c:19]5[c:20]4[cH:21][cH:22][cH:23][cH:24]5)[CH2:26][CH2:27]3)[cH:7][n:8]([CH2:29][C:30]3([CH2:33][O:34][CH3:35])[CH2:31][CH2:32]3)[c:9]2[cH:10]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b0d8ad211edc4ce8905cd91147722020
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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