HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1178183Generated: October 25, 2026
Potassium Carbonate → 2-(1,4,7,10,13-Pentaoxa-16-azacyclooctadecan-16-yl)ethyl benzoate
https://huagongshe.com/reaction/1178183
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloroethylbenzoate | HCID 95952 | — |
| Reactant | 1,4,7,10,13-Pentaoxa-16-azacyclooctadecane | HCID 118578 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(1,4,7,10,13-Pentaoxa-16-azacyclooctadecan-16-yl)ethyl benzoate | HCID 58974467 | 778.6% |
Reaction Steps
A mixture of 26.3 g of 1-aza-18-crown-6, 19.9 g of 2-chloroethyl benzoate, 21.0 g of potassium carbonate, and 60 g of N,N-dimethylformamide was stirred for 10 hours at 80° C. The reaction mixture was subjected to conventional aqueous work-up and purification by column chromatography. There was obtained 320 g of 2-(1,4,7,10,13-pentaoxa-16-azacyclo-octadecan-16-yl)ethyl benzoate (yield 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07276324B2 |
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| Source dataset | uspto-grants-2007_10 |
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| ORD ID | ord-b4693368965a4bfe9517c4f333076d06 |
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| Source note | uspto-grants-2007_10 |
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