N-(2-Hydroxyethyl)imidazole → HCID 58974443, compound

HRID 1178184Notes

Reaction equation

HRID 1178184 reaction equation
[N:1]1([CH2:6][CH2:7][OH:8])[CH:5]=[CH:4][N:3]=[CH:2]1.[CH:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][C:10]=1[C:19](Cl)=[O:20]>>[CH:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][C:10]=1[C:19]([O:8][CH2:7][CH2:6][N:1]1[CH:5]=[CH:4][N:3]=[CH:2]1)=[O:20]

Participants

3

Reactant 2

HCID 74168N-(2-Hydroxyethyl)imidazoleHCID 752462-Naphthoyl chloride

Product 1

HCID 58974443HCID 58974443, compoundYield 81%

Procedure

The procedure of Synthesis Example 1 was repeated except that 2-(1H-imidazol-1-yl)ethanol was used instead of the triethanolamine, and 2-naphthoyl chloride was used instead of the benzoyl chloride, to give 2-(1H-imidazol-1-yl)ethyl 2-naphthalenecarboxylate in a yield of 81%.

Workup

  1. customThe procedure of Synthesis Example 1

Sources & evidence

ORD record
ord-a7d9a462b0cf4b75b180d0c552ebfe50
Source dataset
uspto-grants-2007_10
Patent number
US07276324B2

Reaction notes

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