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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1178239Generated: October 31, 2026

4-(5-chloro-[1H]-indol-3-yl)-piperidine → HCID 131724868, compound

https://huagongshe.com/reaction/1178239

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-chloro-[1H]-indol-3-yl)-piperidineHCID 12831375—
ReactantHCID 12992363HCID 12992363—
ProductHCID 131724868HCID 131724868—

Reaction Steps

from 5-chloro-3-(piperidin-4-yl)-1H-indole and 1-(3-bromopropan-1-yl)-3,4-dihydroquinolin-2(1H)-one. Mp 142-146° C. 1H NMR (DMSO-d6): 1.95-2.15 (m, 6H); 2.60 (t, 2H); 2.90 (t, 2H); 2.95-3.15 (3H); 3.15-3.20 (m, 2H); 3.55 (d, 2H); 3.95 (t, 2H); 7.00-7.10 (m, 2H); 7.20-7.30 (m, 4H); 7.35 (d, 1H); 7.75 (s, 1H), 11.30 (broad s, 1H); 11.15 (s, 1H). MS m/z: 422 (MH+), 188.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07276508B2
Source datasetuspto-grants-2007_10
ORD IDord-bfa290c1b45c4f28a10bff5fa5715ba9
Source noteuspto-grants-2007_10