Thiophenol → HCID 22320508, compound

HRID 1178294Notes

Reaction equation

Cl[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][NH:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[N:11]=[CH:10][C:9]=1[N+:18]([O-:20])=[O:19].[C:21]1([SH:27])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[N+:18]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:8]=1[NH:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][S:27][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2)([O-:20])=[O:19]

Participants

Reactant 2

HCID 7969Thiophenol

HCID 22320534HCID 22320534, compound

Product 1

HCID 22320508HCID 22320508, compound

Procedure

Using the general method of Example 37 Part D, N-(5-chloropentyl)-3-nitroquinolin-4-amine (10 g, 34 mmol) was reacted with benzenethiol (1.1 eq) to provide 12.6 g of 3-nitro-N-[5-(phenylthio)pentyl]quinolin-4-amine as a solid.

Sources & evidence

ORD record: ord-45abd1bcf0f0465e91056588897afb0b
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07276515B2

Reaction notes

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