3-Phenylprop-2-enoyl chloride → HCID 131726618, compound

Participants

Reaction Conditions

Reaction Steps

1.33 mmol of cinnamoyl chloride are added to a previously cooled solution of 0.30 mmol of the compound of Example 4 in 4 ml of pyridine. After stirring at 0° C. for 90 minutes, the reaction mixture is evaporated under reduced pressure. Chromatography over silica gel (cyclohexane, and then cyclohexane/acetone: 94/6 to 90/10) allows the expected product to be isolated.

Provenance & Evidence