Acetyl chloride → HCID 23118687, compound

Participants

Reaction Steps

2-(5-Acetyl-5,6-dihydro-phenanthridin-6-yl)-cyclopentanone was prepared from phenanthridine, acetyl chloride, and 1-(trimethylsilyloxy)cyclopentene according to GP 2. Yield, 25%. 1H-NMR (DMSO-d6): δ=1.23-1.38 (m, 2H), 1.43-1.61 (m, 1H), 1.67-1.81 (m, 1H), 1.81-2.27 (m, 6H), 6.15 (s, 1H), 7.21-7.56 (m, 6H), 7.85-7.97 (m, 2H); (+)-ESI-MS: m/z=306 [M+H]+, 222, 180.

Provenance & Evidence