HCID 11586442, compound → HCID 11280931, compound

HRID 1178774Notes

Reaction equation

HRID 1178774 reaction equation
[N:1]1([C:7]([C:9]2[CH:10]=[C:11]([CH:32]=[CH:33][CH:34]=2)[CH2:12][NH:13][CH2:14][CH2:15][O:16][C:17]2[CH:18]=[C:19]([O:23][C:24](=O)[C:25]3C=CC=CC=3)[CH:20]=[CH:21][CH:22]=2)=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:35](OC1C=CC=CC=1NCCN)(C)C>>[CH:24]([O:23][C:19]1[CH:18]=[C:17]([CH:22]=[CH:21][CH:20]=1)[O:16][CH2:15][CH2:14][NH:13][CH2:12][C:11]1[CH:10]=[C:9]([C:7]([N:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)=[O:8])[CH:34]=[CH:33][CH:32]=1)([CH3:35])[CH3:25]

Participants

3

Reactant 2

HCID 11586442HCID 11586442, compoundHCID 86596743HCID 86596743, compound

Product 1

HCID 11280931HCID 11280931, compound

Procedure

Benzoic acid 3-{2-[3-(piperidine-1-carbonyl)-benzylamino]-ethoxy}-phenyl ester. The title compound was prepared as in Example 1, steps D and E, substituting benzoic acid 3-(2-amino-ethoxy)-phenyl ester for N1-(2-isopropoxy-phenyl)-ethane-1,2-diamine in step E. MS (ESI): mass calculated for C28H30N2O4, 458.22. m/z found, 459.2 [M+H]+, 481.2 [M+Na]+.

Sources & evidence

ORD record
ord-6e9b74e5ff3d42e590f2cfa936e6d701
Source dataset
uspto-grants-2007_10
Patent number
US07276610B2

Reaction notes

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