反应详情

温度

0 °C

To a solution of methyl 1-phenylcyclopent-3-enecarboxylate (298 mg) in ether (10 mL) at 0° C. was added lithium aluminum hydride (1.0 M solution in ether, 1.48 mL), and the resulting suspension was stirred at 0° C. for 30 min. The reaction was quenched with saturated sodium sulfate and then diluted with ether (100 mL). Anhydrous sodium sulfate was added, and the ether solution was filtered. The filtrate was evaporated in vacuo to give the title compound as an oil (257 mg). 1H NMR (400 MHz, CDCl3) δ 2.70 (4H, s), 3.54 (2H, d, J=5.6 Hz), 5.75 (1H, s), 7.22-7.35 (5H, m).

1. customThe reaction was quenched with saturated sodium sulfate
2. additiondiluted with ether (100 mL)
3. additionAnhydrous sodium sulfate was added
4. filtrationthe ether solution was filtered
5. customThe filtrate was evaporated in vacuo