Potassium Cation → [2-(3-Thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-(2-trifluoromethylbenzyl)-amine

HRID 117890Notes

Reaction equation

HRID 117890 reaction equation
[Br:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1.[C:19](=[O:20])([O-:21])[O-:22].[CH3:37][C:38]#[N:39].[F:25][C:26]([c:27]1[c:28]([CH2:29][NH2:30])[cH:31][cH:32][cH:33][cH:34]1)([F:35])[F:36].[K+:23].[K+:24]>>[CH2:2]([CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1)[NH:30][CH2:29][c:28]1[c:27]([C:26]([F:25])([F:35])[F:36])[cH:34][cH:33][cH:32][cH:31]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 764472-(Trifluoromethyl)benzylamineHCID 219835823-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

Product 1

HCID 21983566[2-(3-Thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-(2-trifluoromethylbenzyl)-amine

Sources & evidence

ORD record
ord-a55582d8ef0949809fce8d348240be7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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